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"Microfluidic systems for life science applications”

2016-06-01

Dr. Maria Tenje
Department of Engineering Sciences, Uppsala University

Thursday, June 2nd 2016, 15:15 in BMC C2:305


Microfluidics is the method to precisely control liquids in small channels and it is a research field that first saw daylight in the late 1990’s and has since then rapidly expanded. Microfluidics is a very attractive research platform for chemical analysis and biological assays as it requires minute sample volumes and significantly reduces analysis time due to its short diffusion distances. Microfluidic channels can be fabricated in a range of materials, such as silicon, glass and polymers.

I have been using different microfluidic systems in my research during the last 10 years and in this presentation I will share my experiences with you. I will describe a microfluidic platform developed during my PhD work used for chemical functionalisation of mechanical biosensors. This system was fabricated in the inherently hydrophobic material SU8 and relied upon capillary pumping, which was a challenge to combine. More recently I used a microfluidic system in my research to perform a wash-step of blood components, by integrated ultrasound into the microfluidic channel. Today, my research group is developing novel manipulation approaches in droplet microfluidics and developing in vitro models of biological barriers by culturing cells in microfluidic channels.

I hope that I will be able to share my excitement about microfluidic systems with you and show how they can be used for a range of different applications.

Dr. Maria Tenje joined Uppsala University in 2014 upon an open call made by the Faculty of Science & Engineering to attract young talented researchers to the university and today she holds a position as Senior Lecturer at the Department of Engineering Sciences where she heads the research activities of microtechnology solutions for life sciences within the Program of Microsystems Technology. Before joining Uppsala University she was a researcher at Lund University (still holds part-time position there) after having received her PhD degree in 2007 from the Technical University of Denmark. In 2010 Dr. Tenje was awarded the L’Oréal-UNESCO “For Women in Science” prize in Denmark. Dr. Tenje is also associated with the SciLifeLab and is a member of the Young Academy of Sweden. Her main research interests are microsystem engineering and how to utilise microfabrication solutions to solve challenging research questions in collaboration with biologists and medical researchers.

Host: Sebastian Barg (sebastian.barg@mcb.uu.se)