Samtliga publikationer från MCB

Soluble Klotho protects against glomerular injury through regulation of ER stress response

Charrin, Emmanuelle; Dabaghie, Dina; Sen, Ilke; Unnersjö Jess, David et al.

Ingår i Communications Biology, 2023.

DOI för Soluble Klotho protects against glomerular injury through regulation of ER stress response Ladda ner fulltext (pdf) av Soluble Klotho protects against glomerular injury through regulation of ER stress response

Studies on alpha-synuclein and islet amyloid polypeptide interaction

Wang, Ye; Bergström, Joakim; Ingelsson, Martin; Westermark, Gunilla

Ingår i Frontiers in Molecular Biosciences, 2023.

DOI för Studies on alpha-synuclein and islet amyloid polypeptide interaction Ladda ner fulltext (pdf) av Studies on alpha-synuclein and islet amyloid polypeptide interaction

Proteotoxicity and Phenotypic Variability of ATTR Amyloidosis in Drosophila Melanogaster Model

Gu, Xiaohong; Westermark, Gunilla T.

Introducing or removing heparan sulfate binding sites does not alter brain uptake of the blood-brain barrier shuttle scFv8D3

de la Rosa, Andres; Metzendorf, Nicole G.; Morrison, Jamie; Faresjö, Rebecca et al.

Ingår i Scientific Reports, 2022.

DOI för Introducing or removing heparan sulfate binding sites does not alter brain uptake of the blood-brain barrier shuttle scFv8D3 Ladda ner fulltext (pdf) av Introducing or removing heparan sulfate binding sites does not alter brain uptake of the blood-brain barrier shuttle scFv8D3

A validation of ultrasound with histology for measurement of abdominal aortic aneurysm in mice

Öberg, Veronika

2023.

Amyloid-beta accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

Zyśk, Marlena; Beretta, Chiara; Naia, Luana; Dakhel, Abdulkhalek et al.

Ingår i Journal of Neuroinflammation, 2023.

DOI för Amyloid-beta accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism Ladda ner fulltext (pdf) av Amyloid-beta accumulation in human astrocytes induces mitochondrial disruption and changed energy metabolism

Impact of intraspecific variation in teleost fishes: aggression, dominance status and stress physiology

Winberg, Svante; Sneddon, Lynne

Ingår i Journal of Experimental Biology, 2022.

DOI för Impact of intraspecific variation in teleost fishes: aggression, dominance status and stress physiology

Plasma expansion and renal perfusion in critical COVID-19 with AKI: a prospective case control study

Luther, Tomas; Eckerbom, Per; Cox, Eleanor; Lipcsey, Miklós et al.

Renal mitochondrial dysfunction in ovine experimental Sepsis Associated Acute Kidney Injury

Luther, Tomas; Bülow Anderberg, Sara; Persson, Patrik; Franzén, Stephanie et al.

2022.

Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine

Ngamjariyawat, Anongnad; Cen, Jing; Said, Romain; Incedal, Ceren et al.

Ingår i Frontiers in Endocrinology, 2023.

DOI för Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine Ladda ner fulltext (pdf) av Metabolic stress-induced human beta-cell death is mediated by increased intracellular levels of adenosine

Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Cotman, Andrej Emanuel; Durcik, Martina; Tiz, Davide Benedetto; Fulgheri, Federica et al.

Ingår i Journal of Medicinal Chemistry, s. 1380-1425, 2023.

DOI för Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa Ladda ner fulltext (pdf) av Discovery and Hit-to-Lead Optimization of Benzothiazole Scaffold- Based DNA Gyrase Inhibitors with Potent Activity against Acinetobacter baumannii and Pseudomonas aeruginosa

Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells

Kundu, Snehangshu; Nunes, Luís; Adler, Jeremy; Mathot, Lucy et al.

Preclinical evaluation of Affibody molecule ¹⁸F-TZ-Z_AM106 for PET imaging of DGCR2

Cheung, Pierre; Thorngren, Julia; Zhang, Bo; Vasylovska, Svitlana et al.

Local PI(4,5)P2 signaling inhibits fusion pore expansion during exocytosis.

Omar-Hmeadi, Muhmmad; Gucek, Alenka; Barg, Sebastian

Ingår i Cell reports, s. 112036-, 2023.

DOI för Local PI(4,5)P2 signaling inhibits fusion pore expansion during exocytosis.

Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction.

Edvinsson, Åsa; Bränn, Emma; Hellgren, Charlotte; Freyhult, Eva et al.

Ingår i Psychoneuroendocrinology, s. 15-25, 2017.

DOI för Lower inflammatory markers in women with antenatal depression brings the M1/M2 balance into focus from a new direction.

An insulin hypersecretion phenotype precedes pancreatic beta cell failure in MODY3 patient-specific cells

Hermann, Florian M.; Kjaergaard, Maya Friis; Tian, Chenglei; Tiemann, Ulf et al.

Ingår i Cell Stem Cell, s. 38-51, 2023.

DOI för An insulin hypersecretion phenotype precedes pancreatic beta cell failure in MODY3 patient-specific cells Ladda ner fulltext (pdf) av An insulin hypersecretion phenotype precedes pancreatic beta cell failure in MODY3 patient-specific cells

Hoverfly (Eristalis tenax) pursuit of artificial targets

Thyselius, Malin; Ogawa, Yuri; Leibbrandt, Richard; Wardill, Trevor J. et al.

Ingår i Journal of Experimental Biology, 2023.

DOI för Hoverfly (Eristalis tenax) pursuit of artificial targets

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

Dawed, Adem Y.; Mari, Andrea; Brown, Andrew; McDonald, Timothy J. et al.

Ingår i The Lancet Diabetes and Endocrinology, s. 33-41, 2023.

DOI för Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials Ladda ner fulltext (pdf) av Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials

Quantitative imaging of doxorubicin diffusion and cellular uptake in biomimetic gels with human liver tumor cells

Degerstedt, Oliver; O'Callaghan, Paul; Lerma Clavero, Ada; Gråsjö, Johan et al.

Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study

Karlsson, Philip A.; Pärssinen, Julia; Danielsson, Erik A.; Fatsis-Kavalopoulos, Nikos et al.

Ingår i Frontiers in Medicine, 2023.

DOI för Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study Ladda ner fulltext (pdf) av Antibiotic use during coronavirus disease 2019 intensive care unit shape multidrug resistance bacteriuria: A Swedish longitudinal prospective study

Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Jin, Yi; Ding, Yindi; Richards, Mark; Kaakinen, Mika et al.

Ingår i Nature Cardiovascular Research, s. 1156-1173, 2022.

DOI för Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis

Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19: A Swedish Cohort Study

Asif, Sana; Frithiof, Robert; Larsson, Anders; Franzén, Stephanie et al.

Ingår i Biomedicines, 2023.

DOI för Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19: A Swedish Cohort Study Ladda ner fulltext (pdf) av Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19: A Swedish Cohort Study

Deletion of Notch3 Impairs Contractility of Renal Resistance Vessels Due to Deficient Ca2+ Entry

Helle, Frank; Hultström, Michael; Kavvadas, Panagiotis; Iversen, Bjarne et al.

Ingår i International Journal of Molecular Sciences, 2022.

DOI för Deletion of Notch3 Impairs Contractility of Renal Resistance Vessels Due to Deficient Ca2+ Entry Ladda ner fulltext (pdf) av Deletion of Notch3 Impairs Contractility of Renal Resistance Vessels Due to Deficient Ca2+ Entry

Clinical potential of eosinophil-derived neurotoxin in asthma management.

Malinovschi, Andrei; Rydell, Niclas; Fujisawa, Takao; Borres, Magnus P et al.

Ingår i Journal of Allergy and Clinical Immunology, 2022.

DOI för Clinical potential of eosinophil-derived neurotoxin in asthma management.

Vision: Flies move their eyes

Nordström, Karin; Barron, Andrew B.

Ingår i Current Biology, s. R20-R22, 2023.

DOI för Vision: Flies move their eyes

Effects of alpha(2)-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum

Nylander, Olof; Sjöblom, Markus; Sedin, John; Dahlgren, David

Ingår i PLOS ONE, 2022.

DOI för Effects of alpha(2)-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum Ladda ner fulltext (pdf) av Effects of alpha(2)-adrenoceptor stimulation on luminal alkalinisation and net fluid flux in rat duodenum

Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

Bruhn-Olszewska, Bozena; Davies, Hanna; Sarkisyan, Daniil; Juhas, Ulana et al.

Ingår i Genome Medicine, 2022.

DOI för Loss of Y in leukocytes as a risk factor for critical COVID-19 in men Ladda ner fulltext (pdf) av Loss of Y in leukocytes as a risk factor for critical COVID-19 in men

Extracellular membrane vesicles from Limosilactobacillus reuteri strengthen the intestinal epithelial integrity, modulate cytokine responses and antagonize activation of TRPV1

Pang, Yanhong; Lundberg, Ludwig Ermann; Forsberg, Manuel Mata; Ahl, David et al.

Ingår i Frontiers in Microbiology, 2022.

DOI för Extracellular membrane vesicles from Limosilactobacillus reuteri strengthen the intestinal epithelial integrity, modulate cytokine responses and antagonize activation of TRPV1 Ladda ner fulltext (pdf) av Extracellular membrane vesicles from Limosilactobacillus reuteri strengthen the intestinal epithelial integrity, modulate cytokine responses and antagonize activation of TRPV1

Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency

Guan, Nan; Kobayashi, Hanako; Ishii, Ken; Davidoff, Olena et al.

Ingår i Kidney International, s. 108-120, 2022.

DOI för Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency

Pharmacological HIF‐PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

Burmakin, Mikhail; Fasching, Angelica; Kobayashi, Hanako; Urrutia, Andrés A. et al.

Ingår i Acta Physiologica, 2021.

DOI för Pharmacological HIF‐PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease

Koury, Mark J.; Agarwal, Rajiv; Chertow, Glenn M.; Eckardt, Kai‐Uwe et al.

Ingår i American Journal of Hematology, s. 1178-1188, 2022.

DOI för Erythropoietic effects of vadadustat in patients with anemia associated with chronic kidney disease

Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function

Konstantinidis, Evangelos; Portal, Benjamin; Mothes, Tobias J.; Beretta, Chiara et al.

Ingår i Journal of Neuroinflammation, 2023.

DOI för Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function Ladda ner fulltext (pdf) av Intracellular deposits of amyloid-beta influence the ability of human iPSC-derived astrocytes to support neuronal function

Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital

Vesterlund Damjanovic, Justina; Ihse, Elisabet; Thelander, Ulrika; Zancanaro, Alice et al.

Ingår i Upsala Journal of Medical Sciences, 2022.

DOI för Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital Ladda ner fulltext (pdf) av Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital

The β-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signaling.

Sanchez, Gonzalo Manuel; Incedal, Tugce Ceren; Prada, Juan; O'Callaghan, Paul et al.

Ingår i Journal of Cell Biology, 2023.

DOI för The β-cell primary cilium is an autonomous Ca2+ compartment for paracrine GABA signaling.

Quantification of Secretory Granule Exocytosis by TIRF Imaging and Capacitance Measurements.

Omar-Hmeadi, Muhmmad; Liu, Liangwen; Echeverry, Santiago; Barg, Sebastian

Ingår i Methods in Molecular Biology, s. 179-186, 2023.

DOI för Quantification of Secretory Granule Exocytosis by TIRF Imaging and Capacitance Measurements.

Amyloid fibril structure from the vascular variant of systemic AA amyloidosis

Banerjee, Sambhasan; Baur, Julian; Daniel, Christoph; Pfeiffer, Peter Benedikt et al.

Ingår i Nature Communications, 2022.

DOI för Amyloid fibril structure from the vascular variant of systemic AA amyloidosis Ladda ner fulltext (pdf) av Amyloid fibril structure from the vascular variant of systemic AA amyloidosis

Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19

Larsson, Anders O.; Hultström, Michael; Frithiof, Robert; Lipcsey, Miklós et al.

Ingår i International Journal of Molecular Sciences, 2022.

DOI för Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19 Ladda ner fulltext (pdf) av Shrunken Pore Syndrome Is Frequently Occurring in Severe COVID-19

Targeting ER stress in the hepatic tumor microenvironment

Pavlović, Natasa; Heindryckx, Femke

Ingår i The FEBS Journal, s. 7163-7176, 2022.

DOI för Targeting ER stress in the hepatic tumor microenvironment Ladda ner fulltext (pdf) av Targeting ER stress in the hepatic tumor microenvironment

ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function

Schuster, Jens; Klar, Joakim; Khalfallah, Ayda; Laan, Loora et al.

Ingår i Frontiers in Molecular Neuroscience, 2022.

DOI för ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function Ladda ner fulltext (pdf) av ZEB2 haploinsufficient Mowat-Wilson syndrome induced pluripotent stem cells show disrupted GABAergic transcriptional regulation and function

Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis

Grönberg, Annika; Espes, Daniel; Carlsson, Per-Ola; Ludvigsson, Johnny

Ingår i BMJ Open Diabetes Research & Care, 2022.

DOI för Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis Ladda ner fulltext (pdf) av Higher risk of severe hypoglycemia in children and adolescents with a rapid loss of C-peptide during the first 6 years after type 1 diabetes diagnosis

Setting the Stage for Insulin Granule Dysfunction during Type-l-Diabetes: Is ER Stress the Culprit?

Makam, Aishwarya A.; Biswas, Anusmita; Kothegala, Lakshmi; Gandasi, Nikhil

Ingår i Biomedicines, 2022.

DOI för Setting the Stage for Insulin Granule Dysfunction during Type-l-Diabetes: Is ER Stress the Culprit? Ladda ner fulltext (pdf) av Setting the Stage for Insulin Granule Dysfunction during Type-l-Diabetes: Is ER Stress the Culprit?

Dynamic evolution of transient receptor potential vanilloid (TRPV) ion channel family with numerous gene duplications and losses

Morini, Marina; Bergqvist, Christina; Asturiano, Juan F.; Larhammar, Dan et al.

Ingår i Frontiers in Endocrinology, 2022.

DOI för Dynamic evolution of transient receptor potential vanilloid (TRPV) ion channel family with numerous gene duplications and losses Ladda ner fulltext (pdf) av Dynamic evolution of transient receptor potential vanilloid (TRPV) ion channel family with numerous gene duplications and losses

Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up

Larsson, Ing-Marie; Hultström, Michael; Lipcsey, Miklós; Frithiof, Robert et al.

Ingår i Intensive & Critical Care Nursing, 2023.

DOI för Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up Ladda ner fulltext (pdf) av Poor long-term recovery after critical COVID-19 during 12 months longitudinal follow-up

Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Singh, Kailash; Bricard, Orian; Haughton, Jeason; Björkqvist, Mikaela et al.

Ingår i Biomolecules, 2022.

DOI för Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development Ladda ner fulltext (pdf) av Gene Delivery of Manf to Beta-Cells of the Pancreatic Islets Protects NOD Mice from Type 1 Diabetes Development

Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital

Damjanovic Vesterlund, Justina; Ihse, Elisabet; Thelander, Ulrika; Zancanaro, Alice et al.

Ingår i Upsala Journal of Medical Sciences, 2022.

DOI för Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital Ladda ner fulltext (pdf) av Tissue-based diagnosis of systemic amyloidosis: Experience of the informal diagnostic center at Uppsala University Hospital

Subjective swallowing symptoms in COPD - a 2-year follow up

Gonzalez Lindh, Margareta; Ställberg, Björn; Hårdstedt, Maria; Malinovschi, Andrei et al.

2022.

Infectious SARS-CoV-2 is rarely present in the nasopharynx samples collected from Swedish hospitalized critically ill COVID-19 patients.

Ling, Jiaxin; Hickman, Rachel A.; Frithiof, Robert; Hultström, Michael et al.

Ingår i Irish Journal of Medical Science, s. 1-3, 2022.

DOI för Infectious SARS-CoV-2 is rarely present in the nasopharynx samples collected from Swedish hospitalized critically ill COVID-19 patients.

Hypoxia-inducible factor-prolyl hydroxylase inhibitors in the treatment of anemia of chronic kidney disease.

Haase, Volker H

Ingår i KIDNEY INTERNATIONAL SUPPLEMENTS, s. 8-25, 2021.

Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019

Larsson, Anders O.; Hultström, Michael; Frithiof, Robert; Lipcsey, Miklós et al.

Ingår i Acta Anaesthesiologica Scandinavica, s. 213-220, 2023.

DOI för Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019 Ladda ner fulltext (pdf) av Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019

Interacting polymer-modification enzymes in heparan sulfate biosynthesis

Zhang, Tianji; Yu, Mingjia; Li, Honglian; Maccarana, Marco et al.

Ingår i Carbohydrate Polymers, 2023.

DOI för Interacting polymer-modification enzymes in heparan sulfate biosynthesis