Bryndis Birnir

The GABA Lab

The GABA Lab at Uppsala University was established in 2008 by Professor Birnir and focuses on the role of the extracellular signaling molecule GABA (γ-aminobutyric acid) in the brain, in the pancreatic islets and in the blood. In the brain, GABA reduces excitability of neurons and is the main inhibitory neurotransmitter. In the pancreatic islets, GABA modulates insulin and glucagon secretion and promotes maintenance of the cells that make insulin. In the blood, GABA regulates release of both inflammatory and anti-inflammatory molecules from T cells and reduces proliferation of immune cells. GABA appears to be a major homeostatic molecule promoting balance and health. Because of the importance of GABA signaling in physiology, medicines acting on the GABA system are very important in many diseases i.e., psychiatric and neurodegenerative diseases but also epilepsy and diabetes.

Ongoing Projects...

For further information about this research group please contact Bryndis Birnir